This study proposes an innovative distillation setup – based on a novel extractive dividing-wall column (E-DWC) – that is able to concentrate and dehydrate bioethanol in a single step, by integrating all units of the conventional sequence into only one distillation column. In this work, a mixture of 10 %wt ethanol (100 ktpy plant) is concentrated and dehydrated using ethylene glycol as mass separating agent. Rigorous simulations were carried out in Aspen Plus, and for a fair comparison all alternatives were optimized using the reliable sequential quadratic programming (SQP) method. The results show that energy savings of 17 % and a similar decrease in CapEx, are possible for the novel E-DWC alternative, while using a significantly reduced footprint as compared to the conventional separation process.