In order to carry out theoretical analysis and digital simulation for multiphase reactive chromatography, the multiphase and multicomponent reaction chromatography equations are established considering the coupling effect between chemical reaction and multiphase chromatography. The multiphase - multicomponent reaction chromatography equation is solved by using the second order TVD numerical method. The reversible chromatographic process of two-phase four-component is discussed using the second order form with flux limiting factor. The fluctuation image with initial and boundary conditions is analyzed, and the formation mechanism of the wave image is discussed. The results show that after the fluid enters the chromatography, the shock wave will be generated due to the difference of the adsorption property of the component, thus affecting the concentration distribution diagram of the chromatogram.
