Abstract
In this research, optimize ultrasonic-assisted extraction is aimed to obtain phenolics from Paris polyphylla using solvents: Glucose-Lactic acid, Choline-Lactic acid, Glycerol-Lactic acid, Sodium-Lactic acid, Choline-Citric acid, Glycerol-Citric, Sodium-Citric acid, Glucose-Citric acid, and the solvent with the highest extraction capacity for phenolics is Glucose-Lactic acid. Then, single-factor experiments were carried out to study the effect of the process parameters of ultrasonic-assisted extraction on the extraction efficiency of phenolics. The center point response surface model is used to optimize the extraction process with ultrasonic-assisted waves for phenolics recovery from P. polyphylla. The optimal conditions of terpenoids were 450 W of microwave power, 20 % of water content, and 50 mL/g of liquid-to-solid ratio. The results obtained from the model are close to the experimental results, proving that the optimized model is suitable for predicting experimental results. The study provided a green and sustainable approach to acquire bioactive compounds from P. polyphylla .